CLEVELAND -- Just when it seemed like the Red Sox had run out of ways to lose games in the first week, they found some more Wednesday night.
After falling victim to poor starting pitching and an anemic offense in the first four contests, the Red Sox combined poor relief work and a mental lapse to lose 8-4 to the Cleveland Indians, dropping them to 0-5. With a loss in the road trip finale Thursday afternoon, they can return for their home opener with their worst start to a season since 1945.
The Sox trailed 3-2 in the sixth when it all fell apart for them. Dennys Reyes faced three hitters and put all three on base -- two by hit batsman and another by walk. With the bases loaded, Kevin Youkilis couldn't glove a liner by Michael Brantley. Youkilis stepped on third for one force out, but when he threw to the plate, catcher Jason Varitek failed to tag Travis Buck, instead stepping on the plate.
Asdrubal Cabrera then drove a three-run homer into the seats in right off Dan Wheeler, capping a four-run inning.
The Sox stitched together two runs in the second on an infield chopper by Marco Scutaro and an RBI groundout by Jacoby Ellsbury. Adrian Gonzalez added a two-run homer, his first homer as a member of the Red Sox, in the seventh.
Starter Daisuke Matsuzaka allowed three runs in five innings, needing 96 pitches to record 15 outs. The Sox have yet to get a quality start after one full turn through their rotation.
The Red Sox (93-67) look to close in on the No. 2 seed in the A.L. playoffs and home-field advantage in the Division Series with the Cleveland Indians (92-67) with a victory over the Toronto Blue Jays tonight at Fenway Park.
The Red Sox send left-hander Eduardo Rodriguez (3-7, 4.68 ERA) to the mound against left-hander J.A. Happ (20-4, 3.20). Rodriguez is expected to pitch either Game 3 or 4 of the Division Series against the Indians next week.
If both teams finish with 94 wins, the Red Sox hold the tiebreaker over the Indians, based on Boston winning the season series, 4-2. The Indians may have to play a makeup game Monday with the Detroit Tigers.
The Jays are a game behind the Baltimore Orioles for the top A.L. wild-card spot and hold a half-game lead over the Detroit Tigers for the second wild-card spot.
Red Sox shortstop Xander Bogaerts moves back to his customary No. 2 spot in the batting order after hitting sixth Friday night. Right-handed hitting Aaron Hill is at third base and Christian Vazquez catches for Boston.
There will be the second of three ceremonies this weekend to honor retiring Red Sox DH David Ortiz before the game.
Dustin Pedroia 2B
Xander Bogaerts SS
David Ortiz DH
Mookie Betts RF
Hanley Ramirez 1B
Chris Young LF
Jackie Bradley Jr. CF
Aaron Hill 3B
Christian Vazquez C
Eduardo Rodriguez LHP
Devon Travis 2B
Josh Donaldson 3B
Edwin Encarnacion 1B
Jose Bautista DH
Russell Martin C
Troy Tulowitzki SS
Melvin Upton LF
Kevin Pillar CF
Ezequiel Carrera RF
J.A. Happ LHP
Lou Merloni and Dan Shaughnessy discuss Boston Red Sox pitcher Rick Porcello's chance of winning the CY Young award and if his performance on Friday may have lost his chances.