BALTIMORE -- Wins over the Baltimore Orioles aren't guaranteed for the Red Sox. It just seems that way sometimes.
The Orioles snapped a seven-game losing streak against the Red Sox, taking a 3-0 lead after three innings then adding three runs in the eighth off Alfredo Aceves to seal a 5-2 win over the Sox.
Kyle Weiland, facing the Orioles for the second time in his second major league start, allowed three runs over six innings and was tagged with the loss.
The only runs of the night for Boston came on a two-run homer from Jarrod Saltalamacchia in the fifth off Orioles starter Jeremy Guthrie. It was Saltalamacchia's second homer in as many games and eighth since May 15.
After Saltalamacchia's homer, the Sox had only once got a baserunner into scoring position.
Home runs from Derrek Lee and Mark Reynolds in the eighth added on to the lead in the eighth.
The Red Sox (93-67) look to clinch the No. 2 seed in the A.L. playoffs and home-field advantage in the Division Series with the Cleveland Indians (92-67) with a victory over the Toronto Blue Jays tonight at Fenway Park.
The Red Sox (93-67) send left-hander Eduardo Rodriguez (3-7, 4.68 ERA) to the mound against left-hander J.A. Happ (20-4, 3.20). Rodriguez is expected to pitch either Game 3 or 4 of the Division Series against the Indians next week.
The Jays are a game behind the Baltimore Orioles for the top A.L. wild-card spot and hold a half-game lead over the Detroit Tigers for the second wild-card spot.
Red Sox shortstop Xander Bogaerts moves back to his customary No. 2 spot in the batting order after hitting sixth Friday night. Right-handed hitting Aaron Hill is at third base and Christian Vazquez catches for Boston.
There will be the second of three ceremonies this weekend to honor retiring Red Sox DH David Ortiz before the game.
Dustin Pedroia 2B
Xander Bogaerts SS
David Ortiz DH
Mookie Betts RF
Hanley Ramirez 1B
Chris Young LF
Jackie Bradley Jr. CF
Aaron Hill 3B
Christian Vazquez C
Eduardo Rodriguez LHP
Devon Travis 2B
Josh Donaldson 3B
Edwin Encarnacion 1B
Jose Bautista DH
Russell Martin C
Troy Tulowitzki SS
Melvin Upton LF
Kevin Pillar CF
Ezequiel Carrera RF
J.A. Happ LHP
Lou Merloni and Dan Shaughnessy discuss Boston Red Sox pitcher Rick Porcello's chance of winning the CY Young award and if his performance on Friday may have lost his chances.