David Ortiz became the eighth active player to reach the milestone and moved into 49th place on the all-time homer list with his 400th home run.
The Red Sox manager said that pitcher Aaron Cook gave a good performance, but the team failed to 'help him out with the runs.'
The Red Sox mustered just three hits Wednesday afternoon while suffering their first sweep in Oakland since 2008.
After an impressive stint in Pawtucket, Justin Germano is available to throw for the Red Sox. He'll likely come out of the bullpen.
Darnell McDonald was designated for assignment by the Red Sox last weekend. Now he's a member of the Yankees.