TORONTO -- What began so well for the Red Sox Wednesday night ended horribly.
The Sox staked Clay Buchholz to a 3-0 lead three batters into the game, but Buchholz turned in his worst outing since coming off the disabled list, twice surrendering leads in a 6-4 loss to the Toronto Blue Jays.
Consecutive doubles by Daniel Nava and Xander Bogaerts in the fifth off Toronto starter R.A. Dickey gave the Sox a 4-3 lead.
But in the sixth, Buchholz (four walks, two hits batsman) issued a free pass to No. 7 hitter Josh Thole and a run-scoring triple to No. 8 hitter Ryan Goins, tying the score.
When Buchholz struck out Anthony Gose for the second out, he seemed poised to escape with the score tied. But Xander Bogaerts fielded a routine grounder by Jose Reyes and skipped a throw in the dirt that Mike Napoli couldn't glove and Gose scored the go-ahead run.
The Jays tacked on another run in the seventh when Jose Bautista greeted reliever Andrew Miller by hammering his first pitch out to left-center.
The Sox had struck early against Dickey, with Shane Victorino and Dustin Pedroia singling and David Ortiz hammering a pitch to the third deck in right for his fourth homer in the series. The three-run shot also gave Ortiz 1,501 RBI in his career.
But Buchholz wasted no time handing the lead back to the home team. Eight hitters came to the plate against him in the bottom of the inning. Bautista doubled home the first run. A second run crossed the plate on a fielder's choice to first and Thole doubled into the left field corner for the third.
STAR OF THE GAME: Jose Bautista
Bautista knocked in the first Toronto run of the game in the first with an RBI double and provided the final one, too, with a solo homer off Andrew Miller in the seventh. He had two hits, two RBI and two runs scored.
HONORABLE MENTION: Aaron Sanchez
The Blue Jays brought up Sanchez, their best pitching prospect, from the minors Tuesday and he made an impressive debut. Flashing a fastball in the upper 90s -- quite a contrast from knuckleballer R.A. Dickey, who started -- and retired all six hitters he faced, two by strikeouts.
GOAT OF THE GAME: Clay Buchholz
Buchholz had himself a 3-0 lead three batters into the game, but quickly gave it back in the bottom of the inning. He later squandered another one-run lead. After walking just one batter in his last 35 2/3 innings, he walked four and hit two others.
TURNING POINT: Leading 5-4 in the bottom of the sixth, Buchholz walked the No. 7 hitter and gave up a run-scoring -- and game-tying -- triple to No. 8 hitter Ryan Goins.
BY THE NUMBERS: The error by Xander Bogaerts in the sixth was his ninth in 38 games at third base.
QUOTE OF NOTE: ""I let that lead go. I'll take the blame for this one, for sure." - Clay Buchholz.