BOSTON -- Entering Tuesday's game, the Red Sox bullpen had compiled a 1.98 ERA for the past six weeks, the lowest mark for any bullpen in the big leagues.
Boston's relievers picked a bad night for a rare meltdown.
In the tenth inning, after a game-tying two-run home run over the Wall in the bottom of the ninth by Jarrod Saltalamacchia, Alfredo Aceves allowed two runs on three hits in his second inning of work and the Red Sox lost, 8-6.
The Boston bullpen lost a lead in the seventh inning as well. With the Sox clinging to a 4-3 lead, Scott Atchison and Matt Albers combined to allow two runs (plus an inherited runner) on four hits as the Baltimore Orioles overtook the Sox for a 6-4 victory.
The two runs against Atchison brought an end to a scoreless streak that had lasted 19 23 innings.
The Red Sox had taken their first lead of the night in the bottom of the sixth when Mike Aviles singled home one run and a sacrifice fly by Scott Podsednik accounted for another.
The Orioles had taken advantage of an error by Aviles in the third to allow two unearned runs. The Sox pulled even in the fifth when the Orioles committed an error of their own.
Jon Lester pitched into the seventh and was charged with four runs, two of them earned.
Aviles led the Red Sox offense with three hits while Podsednik added two, plus a sacrifice fly and a sacrifice bunt.
Pablo Sandoval hit his fourth home run of the spring and Rusney Castillo had three hits to lead a Red Sox split squad to a 7-5 victory over the Tampa Bay Rays on Saturday in Port Charlotte, Fla.
Sandoval, who has won back his third base job after missing nearly all of last season following surgery on his left shoulder, connected for a three-run shot, batting right-handed, against Rays starter Ian Snell in the fifth inning. The switch-hitting Sandoval had abandoned hitting right-handed in 2015, his last full season with the Red Sox.
He's hitting .353 this spring with a 1.051 OPS and 19 RBI.
Castillo, the Cuban outfielder signed to a seven-year, $72 million deal late in 2014 but again likely headed for Triple-A Pawtucket, went 3-for-4 and is hitting .368 this spring. Catcher Blake Swihart, also probably Pawtucket-bound, had two hits and is hitting .325.
Kyle Kendrick strengthened his bid for a spot in the rotation by allowing two runs in six innings and striking out six and Jackie Bradley homered as a Red Sox split squad played to a 3-3 tie with the Philadelphia Phillies on Saturday in Fort Myers, Fla.
Kendrick, 32, a non-roster invitee to spring training, allowed eight hits and a walk in his sixth start this spring. He's been the Red Sox best starter with an ERA of 2.17.
With David Price out until May and lefty Drew Pomeranz still a question mark, Kendrick could find his way into the rotation behind Chris Sale, Rick Porcello, Steven Wright and Eduardo Rodriguez.
Bradley went 2-for-3 with his third homer of the spring. He's hitting .244 in spring training games.
The Phillies pushed across the tying run in the ninth off lefty reliever Robby Scott, the first run he's allowed this spring in 10 innings.
The Minnesota Twins host the Red Sox on Sunday at 1:05 at Hammond Stadium in Fort Myers.