MINNEAPOLIS -- For the second time in three days, the Minnesota Twins enjoyed a walk-off win at Andrew Miller's expense.
Aaron Hicks lined a two-out single to left, scoring Kurt Suzuki from second to take a 4-3, 10-inning decision from the Red Sox and leave the Sox with a 3-3 trip through Texas and Minnesota.
Miller had also given up a game-winning, two-run homer in the bottom of the ninth to Chris Parmelee in the series opener.
The Red Sox had rallied from two runs down in the ninth to tie the score off Twins closer Glen Perkins. The Sox got singles from David Ortiz, Jonny Gomes and Mike Carp to load the bases before Will Middlebrooks sliced a single to right, scoring pinch-runner Jonathan Herrera and Gomes.
Jackie Bradley Jr. then took a called third strike with Carp representing the go-ahead run in scoring position.
Phil Hughes, who had had difficulty against the Red Sox as a member of the Yankees (5.70 ERA), limited the Sox to just four hits in the first six innings. Three Minnesota relievers handled an inning each out of the bullpen.
Clay Buchholz allowed 10 hits for the second straight start.
The Twins got to him for three runs in the bottom of the second inning. Kurt Suzuki singled off Will Middlebrooks' glove and Chris Parmelee, who won the game Tuesday with a walk-off homer, hit another two-run homer, staking Hughes to an early lead.
Aaron Hicks walked and went from first-to-third on Eduardo Escobar's single to left, then trotted home on Brian Dozier's sacrifice fly to right.
Buchholz didn't allow another run the rest of the way, but didn't have a single 1-2-3 inning and was finished after six because of a bloated pitch count (107 pitches).
STAR OF THE GAME: Phil Hughes
Hughes had a 5.70 career ERA against the Red Sox while with the Yankees, but pitched like a different person Thursday, limiting them to a single run on five hits -- two of the infield variety -- over six innings.
HONORABLE MENTION: Kurt Suzuki
The Twins catcher had three hits, including the one-out double in the bottom of the 10th then led to the winning run. He also scored a run when he singled ahead of Chris Parmelee, who homered in the second.
GOAT OF THE GAME: Mike Napoli
Three times in five plate appearances, Napoli came up with runners on base and each time, he was retired. He fouled out to first with Xander Bogaerts on first, struck out with pinch-runner Jonathan Herrera on first in the ninth, then fanned in the 10th with Herrera on base again.
TURNING POINT: With the potential go-ahead run in scoring position in the top of the ninth, Jackie Bradley Jr. took a called third strike for the final out of the inning. An inning later, the Red Sox were walking off with an extra-inning loss.
BY THE NUMBERS: The loss dropped the Red Sox to 5-9 in day games this season.
QUOTE OF NOTE: "We felt like, coming out of spring training, we'd be record-wise better than what we are. But we're clearly in the mix.'' --John Farrell after the first quarter of the season.